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Article

Life Course Adiposity and Alzheimer's Disease: A Mendelian Randomization Study.

Journal of Alzheimer's disease : JAD - 1 Jan 2021

Li Xian, Tian Yan, Yang Yu-Xiang, Ma Ya-Hui, Shen Xue-Ning, Chen Shi-Dong, Dong Qiang, Tan Lan, Yu Jin-Tai

Abstract excerpt

BACKGROUND: Several studies showed that life course adiposity was associated with Alzheimer's disease (AD). However, the underlying causality remains unclear. OBJECTIVE: We aimed to examine the causal relationship between life course adiposity and AD using Mendelian randomization (MR) analysis. METHODS: Instrumental variants were obtained from large genome-wide association studies (GWAS) for life course...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34057091
DOI: 10.3233/JAD-210345

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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