Article

A systematic literature review of methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology

2023-05-17

Abstract excerpt

<h4>Background</h4> Diseases diagnosed in adulthood may have antecedents throughout – including prenatal – life. Gaining a better understanding of how exposures at different stages in the lifecourse influence health outcomes is key to elucidating the potential benefits of specific disease prevention strategies. However, confounding is highly likely in studies with earlier life or time-varying exposures. Mendelian...

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Literature Corpus work: ff8a4675-a4f9-51b4-8dd9-cc91f91bc7d9
DOI: 10.1101/2023.05.16.22283780

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