Article

Can the impact of childhood adiposity on disease risk be reversed? A Mendelian randomization study

2019-10-05

Abstract excerpt

<h4>Objective</h4> To evaluate whether early life adiposity has an independent effect on later life disease risk or whether its influence is mediated by adulthood body mass index (BMI). <h4>Design</h4> Two-sample univariable and multivariable Mendelian randomization. <h4>Setting</h4> The UK Biobank (UKB) prospective cohort study and four large-scale genome-wide association study (GWAS) consortia. <h4>Participants<...

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Literature Corpus work: 41196e60-ae6b-5dde-a827-1d14724b7cfc
DOI: 10.1101/19008011

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