Article

Structural and energetic differences between the human RXRα–PPARγ heterodimer with and without DNA binding

2022-06-06

Abstract excerpt

<title>Abstract</title> <p>Structural data of multidomain structures of nuclear receptor complexes provides essential insights into how the quaternary complex impacts the nuclear receptor function. The heterodimeric complex between retinoic X receptor alpha (RXRα) and peroxisome proliferator-activated receptor gamma (PPARγ) is one of the most important and predominant regulatory systems, controlling lipid metabol...

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Literature Corpus work: d78fc6f8-04e1-5016-85b5-309839946660
DOI: 10.21203/rs.3.rs-1724133/v1

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