Article

Amplifying the heat shock response ameliorates ALS and FTD pathology in mouse and human models.

2023-05-15

Abstract excerpt

<title>Abstract</title> <p>Amyotrophic Lateral Sclerosis (ALS) and frontotemporal dementia (FTD) are now known as parts of a disease spectrum with common pathological features and genetic causes. However, as both conditions are clinically heterogeneous, patient groups may be phenotypically similar but pathogenically and genetically variable. Despite numerous clinical trials, there remains no effective therapy for...

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Literature Corpus work: d7636e51-0daf-531c-8c08-738e39a25195
DOI: 10.21203/rs.3.rs-2899750/v1

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