Article

Tumor type and cell type-specific gene expression alterations in diverse pediatric central nervous system tumors identified using single nuclei RNA-seq

2023-02-23

Abstract excerpt

<title>Abstract</title> <p>Central nervous system (CNS) tumors are the leading cause of pediatric cancer death, and these patients have an increased risk for developing secondary neoplasms. Due to the low prevalence of pediatric CNS tumors, major advances in targeted therapies have been lagging compared to other adult tumors. We collected single nuclei RNA-seq data from 35 pediatric CNS tumors and three non-tumor...

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Literature Corpus work: 8a178ab3-4517-5be9-9632-e1261c60b1a4
DOI: 10.21203/rs.3.rs-2517703/v1

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