Article

Correlation Between Molecular Genetic Analysis and Nuclear Pleomorphism in Long-Term Recurrent and Metastatic Chordoma

2026-02-03

Abstract excerpt

<h4>Background: </h4> /Objectives: Recurrences and metastases occur frequently in chordoma and are the main influence on overall survival. However, prognostic biomarkers for recurrence remain limited. This study examines whether quantitative nuclear morphometry captures recurrence evolution and whether it aligns with immunophenotype and genomic profiling. <h4>Methods:</h4> 26 specimens from 12 adults (eight non-re...

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Literature Corpus work: d6dc82af-7762-5e6c-b525-de9bfc5bcb24
DOI: 10.20944/preprints202602.0214.v1

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