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Article

Molecular characteristics of poorly differentiated chordoma

28 May 2019

Abstract excerpt

Pediatric poorly differentiated chordoma is a subtype of chordoma with a much more aggressive clinical course and has been characterized by loss of SMARCB1. This study characterizes the molecular features of these tumors in comparison to conventional chordoma. A search of records between 1990 and 2017 at Massachusetts General Hospital identified two patients with sufficient excess tissue for molecular analysis...

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Identifiers

PMID: 31135077
DOI: 10.1002/gcc.22782

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