Article

From Histology to Multi-Omics: Review of Chordoma Classification and Its Clinical Implications

2026-04-03

Abstract excerpt

Chordoma is a rare malignant neoplasm of the axial skeleton, arising from notochordal remnants. No approved systemic therapies exist and a 10-year overall survival is below 60%. Accurate molecular and pathological classification is a prerequisite for improved prognostication and identification of actionable therapeutic targets, yet molecular classification of chordoma remains significantly less advanced than in ot...

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Literature Corpus work: 9ac5e1cb-16ec-52a3-8baa-7baf8ff75b2d
DOI: 10.20944/preprints202604.0289.v1

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