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Article

Genome-wide DNA methylation profiling of recurrent and non-recurrent chordomas

26 Jan 2015

Abstract excerpt

Chordomas are an aggressive rare type of malignant bone tumors arising from the remnant of the notochord. Chordomas occur mainly in vertebral bones and account for 1-4% of malignant bone tumors. Management and treatment of chordomas are difficult as they are resistant to conventional chemotherapy; therefore, they are mainly treated with surgery and radiation therapy. In this study, we performed DNA methylation...

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Identifiers

PMID: 25621392
DOI: 10.1080/15592294.2015.1006497

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