Article

Single-Cell Transcriptome Profiling Reveals Intratumoral Heterogeneity in Human Chordomas

2021-02-04

Abstract excerpt

<h4>Background: </h4> Chordoma is a rare and aggressive bone tumor with high recurrence. The intra-tumoral heterogeneity of chordomas is poorly understood, limiting the development of effective therapeutic strategies. <h4>Methods: </h4>: Single-cell RNA sequencing was performed to delineate the transcriptomic landscape of chordomas. Six tumor samples of pathologically classical chordomas were obtained, and 33,737...

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Literature Corpus work: 245e1385-d4f8-5503-8f7c-37a594de12f0
DOI: 10.21203/rs.3.rs-167938/v1

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