Article

Cellular and molecular basis of <i>Pf</i> Coronin function in artemisinin resistance in <i>Plasmodium falciparum</i>

2025-09-08

Abstract excerpt

<h4>Summary</h4> Artemisinin-based therapies are central to malaria treatment, but their efficacy is threatened by the emergence of resistant Plasmodium falciparum strains. While the role of Pfkelch13 mutations in clinical resistance is well established, recent reports from Africa implicate Pfcoronin mutations in treatment failure, adding to the complexity of resistance mechanisms. Here, we show that Pf Coron...

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Literature Corpus work: d6dc09f4-bad5-574f-bf75-1ff501b04242
DOI: 10.1101/2025.09.06.674515

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