Article

Iron transport pathways in the human malaria parasite <i>Plasmodium falciparum</i> revealed by RNA-sequencing

2024-04-20

Abstract excerpt

<h4>ABSTRACT</h4> Host iron deficiency is protective against severe malaria as the human malaria parasite Plasmodium falciparum depends on bioavailable iron from its host to proliferate. The essential pathways of iron acquisition, storage, export, and detoxification in the parasite differ from those in humans, as orthologs of the mammalian transferrin receptor, ferritin, or ferroportin, and a functional heme oxy...

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Literature Corpus work: c2cf3c78-4346-5491-87a7-75fdbab0dea1
DOI: 10.1101/2024.04.18.590068

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