Article

MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells

2020-09-03

Abstract excerpt

Recent studies profiling the innate immune signatures in patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suggest that cellular responses to viral challenge impact disease severity. Yet, the molecular events that underlie cellular recognition and response to SARS-CoV-2 infection remains to be elucidated. Here, we find that SARS-CoV-2 replication induces a delayed interferon (IFN)...

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Literature Corpus work: d6d7f1be-6701-56fa-a258-1d9886c4507d
DOI: 10.2139/ssrn.3682826

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