Article

Type I and Type III IFN Restrict SARS-CoV-2 Infection of Human Airway Epithelial Cultures

2020-05-20

Abstract excerpt

<h4>ABSTRACT</h4> The newly emerged human coronavirus, SARS-CoV-2, has caused a pandemic of respiratory illness. The innate immune response is critical for protection against Coronaviruses. However, little is known about the interplay between the innate immune system and SARS-CoV-2. Here, we modeled SARS-CoV-2 infection using primary human airway epithelial (pHAE) cultures, which are maintained in an air-liquid i...

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Literature Corpus work: 0c7d9a4e-1eb3-5beb-b067-b69b34adc7b3
DOI: 10.1101/2020.05.19.105437

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