Article

Differential roles of RIG-I-like receptors in SARS-CoV-2 infection

2021-02-11

Abstract excerpt

The retinoic acid-inducible gene I (RIG-I) and melanoma differentiation-associated protein 5 (MDA5) are the major viral RNA sensors that are essential for activation of antiviral immune responses. However, their roles in severe acute respiratory syndrome (SARS)-causing coronavirus (CoV) infection are largely unknown. Herein we investigate their functions in human epithelial cells, the primary and initial target of...

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Literature Corpus work: fe48d1f3-dad8-5995-bff4-0761e96795a0
DOI: 10.1101/2021.02.10.430677

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