Article

Rare codon translation regulates growth factor-dependent cell proliferation

2025-04-21

Abstract excerpt

In animal cells, growth factor signaling promotes both cell cycle progression and cell growth, but the connection between these two processes is not well understood. Here, we investigated whether cell cycling and cell growth are coupled through protein translation. Using ribosome profiling and mRNA sequencing we examined changes in translational activities in human Retinal Pigment Epithelial (RPE-1) cells as they...

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Literature Corpus work: d6b4b271-453f-54d2-9993-87a772c8c842
DOI: 10.1101/2025.04.17.648825

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