Article

Genes with 5′ terminal oligopyrimidine tracts preferentially escape global suppression of translation by the SARS-CoV-2 Nsp1 protein

2020-09-14

Abstract excerpt

Viruses rely on the host translation machinery to synthesize their own proteins. Consequently, they have evolved varied mechanisms to co-opt host translation for their survival. SARS-CoV-2 relies on a non-structural protein, Nsp1, for shutting down host translation. However, it is currently unknown how viral proteins and host factors critical for viral replication can escape a global shutdown of host translation....

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Literature Corpus work: 3b8d7910-67ac-5ab6-9053-1d44c32b8ede
DOI: 10.1101/2020.09.13.295493

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