Article
Actionable biological programs to enhance EGFR-targeted therapy response unveiled by single-cell lineage tracing in clinically relevant lung cancer models
2025-05-23
Abstract excerpt
Developing high-resolution approaches to capture both tumor architectural clonality and transcriptional state(s) in individual cells within heterogeneous tumor cell populations could shed light on the evolution of pre-existing and newly emergent tumor subclones and their phenotypes, elucidating their trajectories in response to selective pressures such as drug treatment. Reports to date have focused primarily on a...
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Identifiers and source
- Literature Corpus work
- d6b18847-ff21-5c3b-acd2-0cdfb8804573
- DOI
- 10.1101/2025.05.19.654081