Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx Study

8 Jul 2014

Abstract excerpt

The importance of intratumour genetic and functional heterogeneity is increasingly recognised as a driver of cancer progression and survival outcome. Understanding how tumour clonal heterogeneity impacts upon therapeutic outcome, however, is still an area of unmet clinical and scientific need. TRACERx (TRAcking non-small cell lung Cancer Evolution through therapy [Rx]), a prospective study of patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Lung Cancer Treatments and Mutations
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25003521
DOI: 10.1371/journal.pbio.1001906

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tracking Genomic Cancer Evolution for Precision Medicine: The Lung TRACERx StudyPMID 25003521Read ↗

The evolution of lung cancer and impact of subclonal selection in TRACERx.Semantic proximity Read ↗

Genomic evolution of non-small cell lung cancer patient-derived xenograft modelsSemantic proximity Read ↗

Genetic Clonality as the Hallmark Driving Evolution of Non-Small Cell Lung CancerSemantic proximity Read ↗

Revealing the Drivers Underlying Distinct Evolutionary Trajectories in Lung AdenocarcinomaSemantic proximity Read ↗

Revealing the subtyping of non-small cell lung cancer based on genomic evolutionary patterns by multi-region sequencing.Semantic proximity Read ↗

Evolutionary trajectories of small cell lung cancer under therapy.Semantic proximity Read ↗

Comprehensive analysis of tumour initiation, spatial and temporal progression under multiple lines of treatmentSemantic proximity Read ↗

Capturing Genomic Evolution of Lung Cancers through Liquid Biopsy for Circulating Tumor DNASemantic proximity Read ↗

Tracking the Evolution of Non-Small-Cell Lung Cancer.Semantic proximity Read ↗

Molecular portraits of lung cancer evolutionSemantic proximity Read ↗

Representation of genomic intratumor heterogeneity in multi-region non-small cell lung cancer patient-derived xenograft modelsSemantic proximity Read ↗

Phylogenetic and phylodynamic approaches to understanding the evolution of non-small cell lung cancer using single-cell sequencingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.