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Article

The Greatly Under-Represented Role of Smooth Muscle Cells in Atherosclerosis

4 Sept 2023

Abstract excerpt

PURPOSE OF REVIEW: This article summarizes previous and recent research on the fundamental role of arterial smooth muscle cells (SMCs) as drivers of initial and, along with macrophages, later stages of human atherosclerosis. RECENT FINDINGS: Studies using human tissues and SMC lineage-tracing mice have reinforced earlier observations that SMCs drive initial atherogenesis in humans and contribute a multitude of...

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PMID: 37665492
DOI: 10.1007/s11883-023-01145-8

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