Article
BEYOND CONTRACTILITY: PHENOTYPIC SWITCHING OF VASCULAR SMOOTH MUSCLE CELLS IN ATHEROSCLEROSIS.
Georgian medical news - 1 May 2026
Zakharov O, Vasileva A, Idiatullin R, Maslov V, Malashikhina A, Solomonov S, Falicheva A, Ruchkina K, Popov V, Litiuk D, Oshchipok D, Tarusina V, Kulbyakova M, Saryeva A, Torba D, Korotkova S, Sakharova V, Mamutova Z, Yaksun V, Suvorova S
Abstract excerpt
Atherosclerosis is a complex and dynamic vascular disease driven by chronic inflammation, lipid accumulation, and profound cellular remodeling within the arterial wall. Among the cellular components of the atherosclerotic plaque, vascular smooth muscle cells (VSMCs) play a pivotal and increasingly recognized role. VSMCs display a high degree of phenotypic adaptability, enabling dynamic responses to vascular...
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