Endothelial to mesenchymal transition (EndMT) in atherosclerosis: mechanisms, models, and therapies.

doi:10.1093/cvr/cvag145

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Endothelial to mesenchymal transition (EndMT) in atherosclerosis: mechanisms, models, and therapies.

Cardiovascular research - 26 Aug 2026

Ilyas Iqra, Evans Paul C, Berk Bradford C, Offermanns Stefan, Xu Suowen

Abstract excerpt

Endothelial to mesenchymal transition (EndMT) has emerged as a key contributor to the development and progression of atherosclerotic cardiovascular disease. Driven by biomechanical, inflammatory, and metabolic cues within the vascular microenvironment, EndMT leads to the loss of endothelial identity and the acquisition of mesenchymal characteristics, thereby promoting vascular dysfunction and plaque progression....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arteries
Share to Atherosclerosis
Share to Cardiovascular Agents
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endothelial Cells

Share to Phenotype

Share to Plaque, Atherosclerotic

Share to Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 42377924
DOI: 10.1093/cvr/cvag145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.