Article

Genetic Profiling and Early Detection of Type 2 Diabetes Subtypes through Sex-Stratified GWAS and Explainable AI

2025-07-24

Abstract excerpt

Type 2 diabetes (T2D) is a complex and clinically heterogeneous disease. Although clustering approaches have defined clinical subtypes, their genetic and molecular architectures remain poorly understood. Efforts using genome-wide association studies (GWAS) have been constrained by modest sample sizes and conservative significance thresholds, limiting subgroup resolution. Leveraging recent expansions in cohort scal...

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Literature Corpus work: d63fad59-ab7a-539b-93a0-143547374af2
DOI: 10.1101/2025.07.24.25332120

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