Article

NSF is required for diverse endocytic modes by promoting fusion and fission pore closure in secretory cells

2025-08-18

Abstract excerpt

<h4>Summary</h4> The ATPase N-ethylmaleimide-sensitive factor (NSF), known for disassembling SNARE complexes, plays key roles in neurotransmitter release, neurotransmitter (AMPA, GABA, dopamine) receptor trafficking, and synaptic plasticity, and its dysfunction or mutation is linked to neurological disorders. These roles are largely attributed to SNARE-mediated exocytosis. Here, we reveal a previously unrecognize...

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Literature Corpus work: d5d31d27-c961-5d32-89fa-c2762c3b416a
DOI: 10.1101/2025.08.13.670133

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