Article
SNARE interactions in membrane trafficking: a perspective from mammalian central synapses.
BioEssays : news and reviews in molecular, cellular and developmental biology - 1 Oct 2002
Kavalali Ege T
Abstract excerpt
SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) are a large family of proteins that are present on all organelles involved in intracellular vesicle trafficking and secretion. The interaction of complementary SNAREs found on opposing membranes presents an attractive lock-and-key mechanism, which may underlie the specificity of vesicle trafficking. Moreover, formation of the tight...
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