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Article

Sequential SNARE disassembly and GATE-16-GOS-28 complex assembly mediated by distinct NSF activities drives Golgi membrane fusion.

The Journal of cell biology - 24 Jun 2002

Muller Joyce M M, Shorter James, Newman Richard, Deinhardt Katrin, Sagiv Yuval, Elazar Zvulun, Warren Graham, Shima David T

Abstract excerpt

Characterization of mammalian NSF (G274E) and Drosophila NSF (comatose) mutants revealed an evolutionarily conserved NSF activity distinct from ATPase-dependent SNARE disassembly that was essential for Golgi membrane fusion. Analysis of mammalian NSF function during cell-free assembly of Golgi cisternae from mitotic Golgi fragments revealed that NSF disassembles Golgi SNAREs during mitotic Golgi fragmentation. A...

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Identifiers

PMID: 12070132
DOI: 10.1083/jcb.200202082
PMCID: PMC2173554

Genes

NSF

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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