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Nucleosome-mediated conformational switches in micro-eccDNAs

2025-06-18

Abstract excerpt

<h4>ABSTRACT</h4> Extrachromosomal-circular DNA (eccDNA) are circular-DNA elements that are implicated in cellular processes such as genomic diversification and instability, along with other genomic mechanisms. However, their structure and chromatinization state is poorly understood. Here we identified a 358-bp circular micro-eccDNA molecule derived from the human Titin gene, which was selected for this study bas...

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Literature Corpus work
d4f6e780-9bf3-5c64-866a-afe647b932f3
DOI
10.1101/2025.06.14.659616
Open publication

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Nucleosome-mediated conformational switches in micro-eccDNAsDOI 10.1101/2025.06.14.659616
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