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EccBase: A high-quality database for exploration and characterization of extrachromosomal circular DNAs in cancer

1 Jan 2023

Abstract excerpt

Extrachromosomal circular DNAs (eccDNAs) are widely observed in eukaryotes. Previous studies have demonstrated that eccDNAs are essential to cancer progression, and found that they can not only express in normal cells to regulate RNA, but also function differently in different tissues. It is of major interest to conduct computational or experiments assay to elucidate the mechanisms of eccDNA function, uncover key...

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PMID: 37114214
DOI: 10.1016/j.csbj.2023.04.012

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