Article

Beyond the Linear Genome: Comprehensive Determination of the Endogenous Circular Elements in <i>C. elegans</i> and Human Genomes via an Unbiased Genomic-Biophysical Method

2017-04-19

Abstract excerpt

Investigations aimed at defining the 3-D configuration of eukaryotic chromosomes have consistently encountered an endogenous population of chromosome-derived circular genomic DNA, referred to as extrachromosomal circular DNA (eccDNA). While the production, distribution, and activities of eccDNAs remain understudied, eccDNA formation from specific regions of the linear genome has profound consequences on the regula...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b2d42f3a-2792-500b-a3a2-5533bc04d19d
DOI: 10.1101/128686

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Beyond the Linear Genome: Comprehensive Determination of the Endogenous Circular Elements in <i>C. elegans</i> and Human Genomes via an Unbiased Genomic-Biophysical MethodDOI 10.1101/128686Read

Extrachromosomal circular DNA drives dynamic genome plasticity: emerging roles in disease progression and clinical potentialSemantic proximity Read

An Enhancement of Extrachromosomal Circular DNA Enrichment and Amplification to Address the Extremely Low Overlap Between ReplicatesSemantic proximity Read

Extrachromosomal circular DNA: biogenesis, structure, functions and diseasesSemantic proximity Read

Integrating Circle-Seq with transcriptomics reveals genome-wide characterization of extrachromosomal circular DNA for dilated cardiomyopathySemantic proximity Read

Circular DNA elements of chromosomal origin are common in healthy human somatic tissue.Semantic proximity Read

scCircle-seq unveils the diversity and complexity of extrachromosomal circular DNAs in single cellsSemantic proximity Read

Extrachromosomal Circular DNA Orchestrates Genome Heterogeneity and Outcome in Urothelial Bladder CarcinomaSemantic proximity Read

What Is Extrachromosomal Circular DNA and What Does It Do?Semantic proximity Read

Extrachromosomal circular DNA is common in yeast.Semantic proximity Read

Did circular DNA shape the evolution of mammalian genomes?Semantic proximity Read

Circular DNA in the human germline and its association with recombination.Semantic proximity Read

eccDNA Atlas: a comprehensive resource of eccDNA catalogSemantic proximity Read