Article

The human telomeric nucleosome displays distinct structural and dynamic properties

2019-12-19

Abstract excerpt

<h4>ABSTRACT</h4> Telomeres protect the ends of our chromosomes and are key to maintaining genomic integrity during cell division and differentiation. However, our knowledge of telomeric chromatin and nucleosome structure at the molecular level is limited. Here, we aimed to define the structure, dynamics as well as properties in solution of the human telomeric nucleosome. We first determined the 2.2 Å crystal str...

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Literature Corpus work: e7fec365-b201-5b9b-903d-d36fb635440e
DOI: 10.1101/2019.12.18.881755

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