Article

Ramified rolling circle amplification for efficient and flexible synthesis of nucleosomal DNA sequences

2019-06-21

Abstract excerpt

<h4>ABSTRACT</h4> Nucleosomes are a crucial platform for the recruitment and assembly of protein complexes that process the DNA. Mechanistic and structural in vitro studies typically rely on recombinant nucleosomes that are reconstituted using artificial, strong-positioning DNA sequences. To facilitate such studies on native, genomic nucleosomes, there is a need for methods to produce any desired DNA sequence in...

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Literature Corpus work: 83d3a26e-0514-5c73-97ae-7ce21edcccd8
DOI: 10.1101/676528

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