Article

High throughput CRISPR screening identifies genes involved in macrophage viability and inflammatory pathways

2019-10-16

Abstract excerpt

Macrophages are critical cells of the innate immune system involved in the recognition and destruction of invading microbes in addition to the resolution of inflammation and maintenance of homeostasis. Understanding the genes involved in all aspects of macrophage biology is essential to gaining new insights into immune system dysregulation during diseases that range from autoinflammatory to cancer. Here we utilize...

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Literature Corpus work: d4b946e4-6933-507c-848b-5160380b566e
DOI: 10.1101/807164

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