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Cytokinesis Arrest-induced Binucleation of Macrophages Produces Highly Efficient Efferocytes

2026-08-11

Abstract excerpt

<h4>ABSTRACT</h4> Efferocytosis, the phagocytic clearance of dying cells and debris, supports tissue homeostasis, immune tolerance, and inflammation resolution, whereas its failure contributes to autoimmunity, atherosclerosis, aging, and impaired tissue repair. Although many molecular regulators of efferocytosis have been defined, less is known about whether macrophages can be reprogrammed into a distinct cellula...

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Literature Corpus work
3eb9bc1a-572e-5dfb-8675-a70e529200aa
DOI
10.64898/2026.08.10.731793
Open publication

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