Article

CRISPRi Screen Uncovers lncRNA Regulators of Human Monocyte Growth

2024-11-25

Abstract excerpt

Long noncoding RNAs are emerging as critical regulators of biological processes. While there are over 20,000 lncRNAs annotated in the human genome we do not know the function for the majority. Here we performed a high-throughput CRISPRi screen to identify those lncRNAs that are important in viability in human monocytes using the cell line THP1. We identified a total of 38 hits from the screen and validated and cha...

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Literature Corpus work: f9d8ea41-e362-58f8-8915-2699a7761567
DOI: 10.1101/2024.11.25.624758

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