Article

Fhit expression in gastric adenocarcinoma

2000-01-01

Abstract excerpt

BACKGROUND The FHIT gene is inactivated by deletion in a large fraction of human tumors, including gastric carcinomas, and the Fhit protein has been proposed to act as a tumor suppressor in multiple tumor types. A large fraction of gastric adenocarcinomas have lost expression of the candidate tumor suppressor protein, Fhit, whereas normal gastric epithelial cells are strongly positive and Fhit loss has been found...

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Literature Corpus work: d4af3b89-72bd-5365-84c0-5d7e50512fc1
DOI: 10.1002/(sici)1097-0142(20000101)88:1<24::aid-cncr5>3.0.co;2-w

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