Article

Investigation into the role of heterochromatin protein 1 gamma (HP1γ) in gene regulation in mammals

2016-01-01

Abstract excerpt

Heterochromatin protein 1 (HP1) was identified as a key component of the condensed DNA surrounding centromeres in most eukaryotic cells. Genes placed in close proximity to such constitutively dense heterochromatin regions were found to be stochastically silenced in a proportion of the cells leading to variegation of expression, a classical epigenetic phenomenon known as position effect variegation (PEV). Mutagenes...

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Literature Corpus work: d47d871b-0dbb-52f9-8c36-2059b7e04b0d
DOI: 10.25560/58261

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