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Article

Chromatin structure and the regulation of gene expression: the lessons of PEV in Drosophila.

Advances in genetics - 1 Jan 2008

Girton Jack R, Johansen Kristen M

Abstract excerpt

Position-effect variegation (PEV) was discovered in 1930 in a study of X-ray-induced chromosomal rearrangements. Rearrangements that place euchromatic genes adjacent to a region of centromeric heterochromatin give a variegated phenotype that results from the inactivation of genes by heterochromatin spreading from the breakpoint. PEV can also result from P element insertions that place euchromatic genes into...

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Source

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PMID: 18282501
DOI: 10.1016/S0065-2660(07)00001-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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