Article

Neurogenesis inhibition restores cocaine withdrawal-induced depression via Rac1 mediation

2024-11-06

Abstract excerpt

<title>Abstract</title> <p>Mood disorders, such as depression, are strongly associated with cocaine withdrawal, which increases the risk of relapse<sup>1</sup>. Unlike many other addictive substances, cocaine is associated with chronic withdrawal symptoms, which often manifest as negative emotional states, including anxiety and depression<sup>2–4</sup>. However, the efficacy of antidepressant drugs in treating co...

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Literature Corpus work: d464ff87-afc9-51f3-9ae3-2de2fb58ace9
DOI: 10.21203/rs.3.rs-5140289/v1

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