Article

Reelin deficiency exacerbates cocaine-induced hyperlocomotion by enhancing neuronal activity in the dorsomedial striatum

2022-04-13

Abstract excerpt

The Reln gene encodes for the extracellular glycoprotein Reelin, which regulates several brain functions from development to adulthood, including neuronal migration, dendritic growth and branching, and synapse formation and plasticity. Human studies have implicated Reelin signaling in several neurodevelopmental and psychiatric disorders. Mouse studies using the heterozygous Reeler (HR) mice have shown that reduce...

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Literature Corpus work: 56b10b6f-1522-5d67-953e-6d8b581a3d11
DOI: 10.1101/2022.04.12.488105

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