Article

Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross line

2022-11-01

Abstract excerpt

Unlike single-gene mutations leading to Mendelian conditions, common human diseases are likely emergent phenomena arising from multilayer, multiscale and highly interconnected interactions. Atrial and ventricular septal defects are the most common forms of cardiac congenital anomalies in humans. Atrial septal defects (ASD) show an open communication between left and right atria postnatally, potentially resulting i...

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Literature Corpus work: d40fee14-21cf-5b44-9f22-b3f27afb439d
DOI: 10.1101/2022.10.31.514499

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