Article

Genetic determinants of interventricular septal anatomy and the risk of ventricular septal defects and hypertrophic cardiomyopathy

2021-04-22

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> The interventricular septum (IVS) plays a primary role in cardiovascular physiology and a large proportion of genetic risk remains unexplained for structural heart disease involving the IVS such as hypertrophic cardiomyopathy (HCM) and ventricular septal defects (VSD). <h4>Objectives</h4> We sought to develop a reproducible proxy of IVS structure from standard medical imaging,...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: de8c1254-e078-5818-8238-5a8c42982872
DOI: 10.1101/2021.04.19.21255650

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic determinants of interventricular septal anatomy and the risk of ventricular septal defects and hypertrophic cardiomyopathyDOI 10.1101/2021.04.19.21255650Read

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function.Semantic proximity Read

Genetic architecture of cardiac structure and functionSemantic proximity Read

New Genetic Loci Implicated in Cardiac Morphology and Function Using Three-Dimensional Population Phenotyping.Semantic proximity Read

Genome-wide association study of cardiac structure and systolic function in African Americans: the Candidate Gene Association Resource (CARe) study.Semantic proximity Read

Genetic variants associated with cardiac structure and function: a meta-analysis and replication of genome-wide association data.Semantic proximity Read

Genome-wide association analysis reveals insights into the genetic architecture of right ventricular structure and functionSemantic proximity Read

Genetic and phenotypic architecture of human myocardial trabeculationSemantic proximity Read

Genetic Analysis of Right Heart Structure and Function in 40,000 PeopleSemantic proximity Read

Genetic and phenotypic architecture of human myocardial trabeculation.Semantic proximity Read

Genetic regulation of right ventricular trabeculation identifies developmental and cardiopulmonary pathwaysSemantic proximity Read

Quantitative trait and transcriptome analysis of genetic complexity underpinning cardiac interatrial septation in mice using an advanced intercross lineSemantic proximity Read

Genome-wide association analysis of left ventricular imaging-derived phenotypes identifies 72 risk loci and yields genetic insights into hypertrophic cardiomyopathy.Semantic proximity Read