Article

Genetic architecture of cardiac structure and function

2024-10-08

Abstract excerpt

The heart is the first organ to develop in the mammalian embryo and its architecture is dependent on the spatial organisation of diverse cell types and morphogenetic transformations shaped by biophysical forces. Cardiac remodelling occurs in the mature heart and is a cascade of adaptations in response to stress that are primed in early life. A key question remains as to the processes that regulate the geometry and...

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Literature Corpus work: f114bf2b-a759-5805-ae22-7a0e793ab78a
DOI: 10.1101/2024.10.08.24315091

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