Article

Polyglutamine toxicity assays highlight the advantages of mScarlet for imaging in Saccharomyces cerevisiae

2018-11-26

Abstract excerpt

Development of fluorescent proteins (FPs) enabled researchers to visualize protein localization and trafficking in living cells and organisms. The extended palette of available FPs allows simultaneous detection of multiple fluorescent fusion proteins. Importantly, FPs are originally derived from different organisms from jelly fish to corals and each FP displays its own biophysical properties. Among these propertie...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: d4015c31-d170-52ca-a2a1-2db0b638d266
DOI: 10.12688/f1000research.15829.2

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Polyglutamine toxicity assays highlight the advantages of mScarlet for imaging in Saccharomyces cerevisiaeDOI 10.12688/f1000research.15829.2Read

Polyglutamine toxicity in yeast uncovers phenotypic variations between different fluorescent protein fusions.Semantic proximity Read

Growth assays to assess polyglutamine toxicity in yeast.Semantic proximity Read

Aggregation of expanded polyglutamine domain in yeast leads to defects in endocytosis.Semantic proximity Read

Cytotoxicity of mutant huntingtin fragment in yeast can be modulated by the expression level of wild type huntingtin fragment.Semantic proximity Read

Differential effects of soluble and aggregating polyQ proteins on cytotoxicity and type-1 myosin-dependent endocytosis in yeast.Semantic proximity Read

Comparative Analysis of Mutant Huntingtin Binding Partners in Yeast Species.Semantic proximity Read

Exploiting yeast genetics to inform therapeutic strategies for Huntington's disease.Semantic proximity Read

Expression of an expanded polyglutamine domain in yeast causes death with apoptotic markers.Semantic proximity Read

Systematic High-Content Screening of Fluorescently Tagged Yeast Double Mutant Strains.Semantic proximity Read

Sensitive and Quantitative Three-Color Protein Imaging in Fission Yeast Using Spectrally Diverse, Recoded Fluorescent Proteins with Experimentally-Characterized In Vivo Maturation Kinetics.Semantic proximity Read

Driving amyloid toxicity in a yeast model by structural changes: a molecular approach.Semantic proximity Read

Mutational Scanning of α-Synuclein using a Clickable Protein Tag Reveals Determinants of Membrane-Induced AggregationSemantic proximity Read