Article

RNA- and ATAC-sequencing Reveals a Unique <i>CD83+</i> Microglial Population Focally Depleted in Parkinson’s Disease

2023-05-17

Abstract excerpt

All brain areas affected in Parkinson’s disease (PD) show an abundance of microglia with an activated morphology together with increased expression of pro-inflammatory cytokines, suggesting that neuroinflammation may contribute to the neurodegenerative process in this common and incurable disorder. We applied a single nucleus RNA- and ATAC-sequencing approach using the 10x Genomics Chromium platform to postmortem...

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Literature Corpus work: d398c3fe-9846-5b81-ae1f-5d1c0a2be1ce
DOI: 10.1101/2023.05.17.540842

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