Article

Glial multicellular programs reveal distinct patient stratification in Parkinson's disease

2026-04-30

Abstract excerpt

<title>Abstract</title> <p>Parkinson’s disease (PD) is a neurodegenerative disorder characterized by nigrostriatal degeneration. While the role of glial cells in PD is increasingly recognized, the coordinated multicellular responses driving PD within the dorsal striatum remain poorly understood. By integrating single-nucleus RNA sequencing of 56 donors with targeted spatial transcriptomics, we disentangle regiona...

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Literature Corpus work: 6ece41fc-aad2-575e-a66f-aad7ba1cdaf8
DOI: 10.21203/rs.3.rs-9520754/v1

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