Article

GWAS and meta-analysis identifies multiple new genetic mechanisms underlying severe Covid-19

2022-03-07

Abstract excerpt

Pulmonary inflammation drives critical illness in Covid-19, 1;2 creating a clinically homogeneous extreme phenotype, which we have previously shown to be highly efficient for discovery of genetic associations. 3;4 Despite the advanced stage of illness, we have found that immunomodulatory therapies have strong beneficial effects in this group. 1;5 Further genetic discoveries may identify additional therapeutic targ...

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Literature Corpus work: d35ee62b-43cf-57ab-aba9-ba6b5fb8ec80
DOI: 10.1101/2022.03.07.22271833

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