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Article

Host genetic factors determining COVID-19 susceptibility and severity.

EBioMedicine - 1 Oct 2021

Velavan Thirumalaisamy P, Pallerla Srinivas Reddy, Rüter Jule, Augustin Yolanda, Kremsner Peter G, Krishna Sanjeev, Meyer Christian G

Abstract excerpt

The COVID-19 pandemic caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) poses an unprecedented challenge to humanity. SARS-CoV-2 infections range from asymptomatic to severe courses of COVID-19 with acute respiratory distress syndrome (ARDS), multiorgan involvement and death. Risk factors for disease severity include older age, male sex, increased BMI and pre-existing comorbidities....

Topics

COVID-19
Genetic Predisposition to Disease
Humans
Immunity
Severity of Illness Index

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34655949
DOI: 10.1016/j.ebiom.2021.103629
PMCID: PMC8512556

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34655949-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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