Article

Genetic mechanisms of critical illness in Covid-19

2020-09-25

Abstract excerpt

The subset of patients who develop critical illness in Covid-19 have extensive inflammation affecting the lungs 1 and are strikingly different from other patients: immunosuppressive therapy benefits critically-ill patients, but may harm some non-critical cases. 2 Since susceptibility to life-threatening infections and immune-mediated diseases are both strongly heritable traits, we reasoned that host genetic variat...

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Identifiers and source

Literature Corpus work: 302dc317-ffdd-554a-82c8-82e6c376fc78
DOI: 10.1101/2020.09.24.20200048

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