Article

Whole genome sequence meta-analyses reveal common and rare genetic associations with critical COVID-19

2025-11-21

Abstract excerpt

In susceptible patients, COVID-19 causes life-threatening disease driven by immune-mediated inflammatory lung injury. We have previously shown that multiple common host genetic variants are significantly associated with susceptibility to critical Covid-19, 1;2;3 and in one case, we demonstrated that such variants can inform development of new, effective drug treatment 1;4 . Here we report an association analysis...

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Identifiers and source

Literature Corpus work: 55e06e79-461b-556d-8512-0279b4efce22
DOI: 10.1101/2025.11.19.25340573

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